Uzbekistan is divided into 12 regions (viloyat), one autonomous republic (Karakalpakstan), and the capital city, Tashkent. Each region has unique historical, cultural, and natural attractions, making the country a diverse destination for travelers.

| Division | Capital City | Area (km²) | Population (2022) |
|---|---|---|---|
| Tashkent City | Tashkent | 327 | 2,860,595 |
| Andijan Region | Andijan | 4,303 | 3,253,528 |
| Bukhara Region | Bukhara | 41,937 | 1,976,823 |
| Fergana Region | Fergana | 7,005 | 3,896,395 |
| Jizzakh Region | Jizzakh | 21,179 | 1,443,408 |
| Namangan Region | Namangan | 7,181 | 2,931,056 |
| Navoiy Region | Navoiy | 109,375 | 1,033,857 |
| Kashkadarya Region | Karshi | 28,568 | 3,408,345 |
| Samarkand Region | Samarkand | 16,773 | 4,031,324 |
| Syrdarya Region | Gulistan | 4,276 | 878,591 |
| Surkhandarya Region | Termez | 20,099 | 2,743,201 |
| Tashkent Region | Nurafshon | 15,258 | 2,941,522 |
| Khorezm Region | Urgench | 6,464 | 1,924,163 |
| Karakalpakstan Republic | Nukus | 161,358 | 1,948,488 |
1. Tashkent City
The capital of Uzbekistan and its largest city, Tashkent blends modern infrastructure with Soviet-era charm and Islamic heritage. It features wide boulevards, bazaars, cultural landmarks, and serves as the political and economic hub of the country.
2. Andijan Region
One of the oldest cities in Central Asia and birthplace of Babur, Andijan is a major industrial and agricultural center in the fertile Fergana Valley, with rich traditions and local crafts.
3. Bukhara Region
A historic Silk Road city and UNESCO site, Bukhara is filled with over 140 architectural monuments including ancient mosques and madrasahs, offering a rich Islamic cultural experience.
4. Fergana Region
Known for silk production, vibrant bazaars, and lush landscapes, Fergana is the cultural heart of the Fergana Valley, renowned for its artisanship and historical ties to neighboring countries.
5. Jizzakh Region
Located between steppe and mountains, Jizzakh is ideal for eco-tourism with highlights like Zaamin National Park, Aydarkul Lake, and the Nuratau Mountains.
6. Namangan Region
Namangan is known for flower festivals, traditional knife-making, and its strong horticultural industry. It is a cultural center of the Fergana Valley with deep roots in Uzbek traditions.
7. Navoiy Region
A desert region known for mining and metallurgy, Navoiy features sites like Sarmishsay Petroglyphs and ancient caravan routes across the Kyzylkum Desert.
8. Kashkadarya Region
Home to Shahrisabz, birthplace of Amir Temur (Tamerlane), Kashkadarya is a key region for history, agriculture, and the energy sector in southern Uzbekistan.
9. Samarkand Region
One of the oldest cities in the world and a jewel of the Silk Road, Samarkand is famous for Registan Square, Shah-i-Zinda, and the mausoleum of Tamerlane. A UNESCO World Heritage Site.
10. Surkhandarya Region
Located on the southern border with Afghanistan, this region is rich in Buddhist and Islamic history and offers dramatic mountain landscapes and ancient settlements.
11. Syrdarya Region
A small but important agricultural region, Syrdarya is known for cotton production, reservoirs, and water management initiatives in the country.
12. Tashkent Region
Surrounding the capital, this region features popular natural attractions like Charvak Reservoir and Chimgan Mountains, and is a favorite for domestic tourism.
13. Khorezm Region
Home to the ancient city of Khiva, this region preserves stunning examples of Islamic architecture and serves as a cultural hub along the western Silk Road.
14. Karakalpakstan Republic
An autonomous republic in the northwest, Karakalpakstan is known for the Savitsky Museum in Nukus and the environmental tragedy of the shrinking Aral Sea.